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DMAP‐85: A τ‐Like Protein from Drosophila melanogaster Larvae
(1995)
Abstract: Microtubule‐associated proteins (MAPs) play major regulatory roles in the organization and integrity of the cytoskeletal network. Our main interest in this study was the identification and the analysis of structural ...
Bacterial tubulins A and B exhibit polarized growth, mixed-polarity bundling, and destabilization by GTP hydrolysis
(American Society for Microbiology, 2017)
Bacteria of the genus Prosthecobacter express homologs of eukaryotic alpha- and beta-tubulin, called BtubA and BtubB (BtubA/B), that have been observed to assemble into filaments in the presence of GTP. BtubA/B polymers ...
Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin
(Springer New York LLC, 2016)
© 2015, Springer Science+Business Media New York.In this study, we investigated the role of adducts formation between aminochrome and tubulin and its interference in microtubules assembly and stability in aminochrome-induced ...
Binding of dihydroxynaphthyl aryl ketones to tubulin colchicine site inhibits microtubule assembly
(Elsevier, 2015)
Dihydroxynaphthyl aryl ketones 1e5 have been evaluated for their abilities to inhibit microtubule assembly
and the binding to tubulin. Compounds 3, 4 and 5 displayed competitive inhibition against
colchicine binding, and ...
Tubulin, actin, and tau protein interactions and the study of their macromolecular assemblies
(2002)
The intracellular polymerization of cytoskeletal proteins into their supramolecular assemblies raises many questions regarding the regulatory patterns that control this process. Binding experiments using the ELISA solid ...
Subpopulations of tau interact with microtubules and actin filaments in various cell types
(1995)
It has been demonstrated that microtubule‐associated proteins (MAPs) interact with tubulin in vitro and in vivo. However, there is no clear evidence on the possible roles of the interactions of MAPs in vivo with other ...
The compound 14-keto stypodiol diacetate from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells
(1998)
We investigated the effects of the drug 14-keto-stypodiol diacetate (SDA) extracted from the seaweed product Stypopodium flabelliforme, in inhibiting the cell growth and tumor invasive behavior of DU-145 human prostate ...